New paper: Mucus, slime, and a new way for biological functions to evolve

Published: August 19, 2022

New paper: Mucus, slime, and a new way for biological functions to evolve 

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Petar led this project that we designed with Stefan Ruhl Laboratory on how mucin proteins have evolved. The roles of mucins in different biological processes are becoming more appreciated recently in both evolutionary and biomedical fields. However, their evolution was not known. Our work showed that the gain of exonic repeats on existing precursor genes led to the de novo evolution of mucin function in multiple mammalian lineages. Our manuscript, “A mechanism of gene evolution generating mucin function” is now published in Science Advances.

Our great Charlotte Hsu has prepared a wonderful summary piece. Omer also wrote a piece on The Conversation. Others, such as New Scientist, wrote short pieces on it too.

Mucins are pretty awesome. Next step: figuring out how they contribute to slug sex.

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External resources

Petar is the researcher with Gockumen Lab and Rhul Lab at the University of Buffalo. Led by  Professor Omer Gokcumen , the Gokcumen Lab investigate the contributions of genomic structural variations to human evolution, while Professor Stefan Ruhl's Lab is concerned with how saliva modulates bacterial colonization in the mouth. Refer to their respective websites to learn more.

How to get involved with Petar's work?

If you're new, see the website homepage for ideas on where to start, or browse the Gokcumen Lab website. You can always email Petar at petarpaj@buffalo.edu.

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